Visualisation of DCP, a nerve agent mimic, in Catfish brain by a simple chemosensor

Sarkar, Himadri Sekhar; Ghosh, Ayndrila; Das, Sujoy; Maiti, Pulak Kumar; Maitra, Sudipta; Mandal, Sukhendu; Sahoo, Prithidipa

Visualisation of DCP, a nerve agent mimic, in Catfish brain by a simple chemosensor

Sarkar, Himadri Sekhar; Ghosh, Ayndrila; Das, Sujoy; Maiti, Pulak Kumar; Maitra, Sudipta; Mandal, Sukhendu; Sahoo, Prithidipa

URI: https://vbudspace.lsdiscovery.in/xmlui/handle/123456789/200

Date: 2018-02-21

Abstract:

A chemosensor, 3-aminophenol-based rhodamine conjugate (ARC) has been developed for visualisation of diethylchlorophosphate (DCP), mimic of a chemical warfare agent, in Catfish brain. The simple detection of DCP by “turn-on” fluorescence property of the chemosensor makes it unique for easy and rapid in vivo and in vitro detection of DCP with the detection limit of 5.6 nM.