Abstract:
A p-nitrophenyl based rhodamine probe (NPRB) has
been designed and synthesized for the selective, real-time
detection of Al (III) in aqueous medium with a lower micromolar
range detection limit at physiological pH. All the spectroscopic and
theoretical analysis validated the proposed 1:1 complexation
between NPRB and Al3+ along with an 80-fold enhancement in
fluorescence intensity. Using the “turn on” response of the probe,
binding of NPRB to Al3+ in the brain tissue of adult male zebrafish
(D. rerio) has been visualized through fluorescence microscopy.
